US Patents #6630507 and #6410588 -Cannabinoids

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United States Patent Number 6,630,507

October 7, 2003

Cannabinoids as antioxidants and neuroprotectants

Assignee:    The United States of America as represented by the Department of Health and Human Services (Washington, DC)


Cannabinoids have been found to have antioxidant properties, unrelated to NMDA receptor antagonism. This new found property makes cannabinoids useful in the treatment and prophylaxis of wide variety of oxidation associated diseases, such as ischemic, age-related, inflammatory and autoimmune diseases.

The cannabinoids are found to have particular application as neuroprotectants, for example in limiting neurological damage following ischemic insults, such as stroke and trauma, or in the treatment of neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease and HIV dementia.

Nonpsychoactive cannabinoids, such as cannabidoil, are particularly advantageous to use because they avoid toxicity that is encountered with psychoactive cannabinoids at high doses useful in the method of the present invention. A particular disclosed class of cannabinoids useful as neuroprotective antioxidants is formula (I) wherein the R group is independently selected from the group consisting of H, CH.sub.3, and COCH.sub.3.

The full text is here at

 #2: Use of cannabinoids as anti-inflammatory agents  #6,410,588

Assignee: The Mathilda and Terence Kennedy Institute of Rheumatology (London, GB)
Yissum Research and Development Company of the Hebrew University of Jerusalem (Jerulasem, IL)


The application relates to the identification that cannabinoids, such as cannabidiol can be used to treat inflammatory diseases. Cannabinoids for use in treating inflammatory diseases, methods of treating inflammatory diseases and cannabinoids in combination with pharmaceutically acceptable carriers are claimed.

Full text here at

There are more Cannabis related patents and  applications however these are not assigned to the US Gov.

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US Patent 4189491Tetrahydrocannabinol (THC) in a method of treating glaucoma (1980)

US Patent 4315862Process for preparing cannabichromene (1982)

US Patent 5389375Stable suppository formulations effecting bioavailability of Δ9-THC (1995)

US Patent 5508037Stable suppository formulations effecting bioavailability of Δ9 -THC (1996)

US Patent 6132762Transcutaneous application of marijuana (2000)

US Patent 6328992Cannabinoid patch and method for cannabis transdermal delivery (2001)

US Patent 6383513Compositions comprising cannabinoids (nasal spray) (2002)

US Patent Application 20050042172Administration of medicaments by vaporisation (2002)

US Patent Application 20070151149Methods for altering the level of phytochemicals in plant cells by applying wave lengths of light from 400 nm to 700 nm and apparatus therefore (2004)

US Patent Application 20040049059 A1Method for producing an extract from cannabis plant matter, containing a tetrahydrocannabinol and a cannabidiol and cannabis extracts (2004)

US Patent 6713048Δ9 tetrahydrocannabinol (Δ9 THC) solution metered dose inhalers and methods of use (2004)

US Patent 6974568 – The invention discloses the existence of cannabinoid receptors in the airways, which are functionally linked to inhibition of cough (2005)

US Patent Application 20050266108Methods of purifying cannabinoids from plant material (2005)

US Patent 6949582Method of relieving analgesia and reducing inflamation using a cannabinoid delivery topical liniment (2005)

Grow Hemp for the War

US Patent Application 20050070596Methods for treatment of inflammatory diseases using CT-3 or analogs thereof (2005)

US Patent 6949582Method of relieving analgesia and reducing inflamation using a cannabinoid delivery topical liniment (2005)

US Patent 7088914Device, method and resistive element for vaporizing a medicament (2006)

US Patent 7025992 Administering lipophilic drug through mucous membranes(2006)

US Patent Application 20060242899Method of cultivating plants (2006)

US Patent 7109245Vasoconstrictor cannabinoid analogs (2006)

US Patent Application 20080057117Pharmaceutical Composition Made Up Of Cannabis Extracts (2007)

US Patent 7344736Extraction of pharmaceutically active components from plant materials (2008)

US Patent 7402686Cannabinoid crystalline derivatives and process of cannabinoid purification (2008)

US Patent 7399872Conversion of CBD to Δ-THC and Δ-THC (2008)

US Patent 7622140Processes and apparatus for extraction of active substances and enriched extracts from natural products (2009)

US Patent application 20100249223 New Use for Cannabis Containing Extracts (2010)

US Patent application 20100239693 Cannabinoid Containing Plant Extracts As Neuroprotective Agents (2010)

This page is dedicated to everyone who ever said there’s no such thing as Medical Marijuana. We will remember you.



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